Reid Hoffman is leaving Microsoft’s board to go ‘founder mode’ with startup Manus

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In Brief

Posted:

3:35 PM PDT · June 5, 2026

  • Julie Bort

After a precise profitable decennary connected Microsoft’s board, Reid Hoffman is stepping down, the company announced Thursday. Hoffman joined the committee aft Microsoft bought his institution LinkedIn for $26.2 cardinal successful 2016.

Hoffman was connected Microsoft’s committee erstwhile it invested its archetypal $1 cardinal into OpenAI successful 2019. Hoffman was 1 of OpenAI’s archetypal investors and served connected the exemplary maker’s committee until helium stepped down successful 2023, citing excessively galore imaginable conflicts of involvement to continue. He was besides connected Microsoft’s committee erstwhile the tech elephantine entered into 1 of those non-acquisition, acqui-hire deals for $650 cardinal with his AI startup Inflection AI. Microsoft hired Inflection co-founder Mustafa Suleyman done that deal.

Hoffman said connected a caller occurrence of his “Possible” podcast, portion talking with Microsoft CEO Satya Nadella, that he’s acceptable to spell “founder mode” with his latest AI startup, Manus. Manus is simply a cause find institution that raised implicit $50 million done a couple of effect rounds past year. Hoffman is an investor, arsenic is General Catalyst.

Hoffman is cited arsenic a co-founder of Manus and president of the board, not the CEO, though. That occupation belongs to Dr. Siddhartha Mukherjee, a physician, biologist, and Pulitzer Prize-winning writer of the 2011 publication “The Emperor of All Maladies: A Biography of Cancer.”

Still, Hoffman said he’s excited to springiness Manus much attention.

“One of the things I realized implicit the past period was that, we’re seeing specified advancement with Manus. I request to get backmost to laminitis mode,” helium said. He believes the startup is making advancement on “Move 37” AI, meaning AI that supersedes quality creativity successful chemistry, particularly to combat assorted cancers, helium added.

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